RP-HPLC-Based Quantification of Ciprofloxacin in Active and Pharmaceutical Preparations
Ahsan Zamir Siddiqi, Muneeba Akhtar, Agha Zeeshan Mirza
Abstract
A straightforward and highly sensitive isocratic reversed-phase HPLC technique has been developed for the detection and quantification of ciprofloxacin in pharmaceutical formulations, which has been validated following ICH guidelines. This study introduces a straightforward, cost-effective HPLC technique that delivers accurate results, a low limit of quantification (LOQ), and reduced analysis time. The separation process was performed on a C18 reversed-phase column, using a mobile phase of aceto
Topics & Concepts
CiprofloxacinChromatographyHigh-performance liquid chromatographyChemistryAntibioticsBiochemistryAntibiotics Pharmacokinetics and EfficacyAnalytical Methods in PharmaceuticalsAnalytical Chemistry and Chromatography