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Two adult cases of multisystem inflammatory syndrome associated with SARS-CoV-2

Karolina Mieczkowska, Tian Hao Zhu, Lauren Hoffman, Rachel C. Blasiak, Kenneth Shulman, Mathew R. Birnbaum, David H. Ciocon, Rithu Srikantha, Beth N. McLellan

2021JAAD Case Reports15 citationsDOIOpen Access PDF

Abstract

Since the emergence of SARS-CoV-2 worldwide, various manifestations and sequelae have been reported, including COVID-19-associated Kawasaki-like multisystem inflammatory syndrome in children. This dysregulated immune sequela often presents with features of hypotension or shock, cardiac dysfunction, arterial or venous thromboembolism, gastrointestinal discomfort, and protean skin manifestations.1 More recently, the Centers for Disease Control and Prevention has acknowledged an increasing incidence of multisystem inflammatory syndrome in adults (MIS-A).

Topics & Concepts

MedicineSequelaMultisystem diseaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Incidence (geometry)Coronavirus disease 2019 (COVID-19)DiseaseImmune systemShock (circulatory)Kawasaki disease2019-20 coronavirus outbreakSystemic inflammatory response syndromeIntensive care medicineImmunologyInflammationSepsisPathologyInternal medicineSurgeryInfectious disease (medical specialty)OpticsArteryOutbreakPhysicsKawasaki Disease and Coronary ComplicationsMechanical Circulatory Support DevicesLong-Term Effects of COVID-19