In vitro model for predicting the access and distribution of drugs in the brain using hCMEC/D3 cells
Bárbara Sánchez-Dengra, Isabel González‐Álvarez, Flávia Sousa, Marival Bermejo, Marta González‐Álvarez, Bruno Sarmento
Topics & Concepts
In vitroIn vivoBlood–brain barrierPharmacologyDrugBrain tissuePharmacokineticsDrug deliveryCell cultureChemistryCentral nervous systemBiomedical engineeringMedicineBiologyNeuroscienceBiochemistryBiotechnologyOrganic chemistryGeneticsDrug Transport and Resistance MechanismsNeuroscience and Neuropharmacology ResearchEpilepsy research and treatment