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RIS-UNet: A Multi-Level Hierarchical Framework for Liver Tumor Segmentation in CT Images

Yuchai Wan, Lili Zhang, Murong Wang

2025Entropy6 citationsDOIOpen Access PDF

Abstract

The deep learning-based analysis of liver CT images is expected to provide assistance for clinicians in the diagnostic decision-making process. However, the accuracy of existing methods still falls short of clinical requirements and needs to be further improved. Therefore, in this work, we propose a novel multi-level hierarchical framework for liver tumor segmentation. In the first level, we integrate inter-slice spatial information by a 2.5D network to resolve the accuracy-efficiency trade-off inherent in conventional 2D/3D segmentation strategies for liver tumor segmentation. Then, the second level extracts the inner-slice global and local features for enhancing feature representation. We propose the Res-Inception-SE Block, which combines residual connections, multi-scale Inception modules, and squeeze-excitation attention to capture comprehensive global and local features. Furthermore, we design a hybrid loss function combining Binary Cross Entropy (BCE) and Dice loss to solve the category imbalance problem and accelerate convergence. Extensive experiments on the LiTS17 dataset demonstrate the effectiveness of our method on accuracy, efficiency, and visual results for liver tumor segmentation.

Topics & Concepts

SegmentationComputer scienceCross entropyDiceArtificial intelligenceResidualPattern recognition (psychology)Image segmentationFeature (linguistics)Process (computing)Entropy (arrow of time)Block (permutation group theory)AlgorithmMathematicsGeometryOperating systemPhilosophyQuantum mechanicsLinguisticsPhysicsAdvanced Neural Network ApplicationsRadiomics and Machine Learning in Medical ImagingAI in cancer detection
RIS-UNet: A Multi-Level Hierarchical Framework for Liver Tumor Segmentation in CT Images | Litcius