Cytosolic Escape of Mitochondrial DNA Triggers cGAS-STING Pathway-Dependent Neuronal PANoptosis in Response to Intermittent Hypoxia
Shuying Wang, Jin Tan, Qiang Zhang
Topics & Concepts
Cell biologyProgrammed cell deathMitochondrionBiologyCytosolMitochondrial permeability transition poreStingMitochondrial DNANeurodegenerationApoptosisBiochemistryMedicineInternal medicineGeneDiseaseAerospace engineeringEnzymeEngineeringinterferon and immune responsesInflammasome and immune disordersPeroxisome Proliferator-Activated Receptors