Ni-Catalysed intramolecular reductive aminocarbonylation of 2-haloaryl-tethered nitroarenes for the synthesis of dibenzazepine-based heterocycles
Zhe Chuan Feng, Jun‐An Ma, Chi Wai Cheung
Abstract
A nickel-catalysed intramolecular reductive aminocarbonylation of 2-haloaryl-tethered nitroarenes is developed for rapid access to a variety of dibenzoazepinones and their derivatives.
Topics & Concepts
ChemistryIntramolecular forceMedicinal chemistryCombinatorial chemistryStereochemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsSulfur-Based Synthesis Techniques