Drugging the Phosphoinositide 3-Kinase (PI3K) and Phosphatidylinositol 4-Kinase (PI4K) Family of Enzymes for Treatment of Cancer, Immune Disorders, and Viral/Parasitic Infections
Jacob A. McPhail, John E. Burke
Topics & Concepts
KinasePI3K/AKT/mTOR pathwayBiologyPhosphatidylinositolImmune systemCancerLipid raftCell biologySignal transductionImmunologyGeneticsCalcium signaling and nucleotide metabolismCellular transport and secretionCell death mechanisms and regulation