Demethoxycurcumin mitigates inflammatory responses in lumbar disc herniation via MAPK and NF-κB pathways in vivo and in vitro
Binjie Lu, Xiaolei Chen, Hua Chen, Qian Li, Hongwei Li, Yue Xu, Yuwei Li, Xiaofeng Shen, Rilei Jiang
Topics & Concepts
In vivoInflammationIn vitroPharmacologyNF-κBp38 mitogen-activated protein kinasesChemistryMAPK/ERK pathwayTumor necrosis factor alphaCell biologyBiochemistryBiologySignal transductionImmunologyBiotechnologySpine and Intervertebral Disc PathologyCurcumin's Biomedical ApplicationsPlant Toxicity and Pharmacological Properties