Uncovering dissolution behavior and thermodynamic properties of metronidazole benzoate in twelve mono-solvents by experiments and molecular simulation
Fuhai Yu, Fan Wang, Liang Zhang, Menglong Zhang, Lina Zhou, Chuang Xie, Ying Bao, Wei Chen, Junbo Gong
Topics & Concepts
DissolutionSolubilityChemistryHydrogen bondIntermolecular forceThermodynamicsGibbs free energyPhysical chemistrySolventOrganic chemistryMoleculePhysicsCrystallization and Solubility StudiesChemical and Physical Properties in Aqueous SolutionsCrystallography and molecular interactions