An NO-responsive probe for detecting acute inflammation using NIR-II fluorescence/optoacoustic imaging
Zunpan She, Junjie Chen, Lihe Sun, Fang Zeng, Shuizhu Wu
Abstract
An activatable probe for detecting acute inflammation has been developed. Nitrosation turns electron-donating methylamine into electron-withdrawing methyl- N -nitroso with turn-on NIR-II fluorescence and optoacoustic signals for imaging.
Topics & Concepts
InflammationFluorescencePhotoacoustic imaging in biomedicineFluorescence-lifetime imaging microscopyMedicineOpticsInternal medicinePhysicsNanoplatforms for cancer theranosticsPhotoacoustic and Ultrasonic ImagingAnalytical Chemistry and Sensors