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A large, square-shaped, DNA origami nanopore with sealing function on a giant vesicle membrane

Shoji Iwabuchi, Ibuki Kawamata, Satoshi Murata, Shin‐ichiro M. Nomura

2021Chemical Communications43 citationsDOIOpen Access PDF

Abstract

. When the nanopore is added to a giant vesicle that mimics a cell membrane, the permeation of large external hydrophilic fluorescent molecules is observed. Furthermore, the addition of up to four ssDNA strands enables size-based selective transport of molecules. A controllable artificial nanopore should facilitate the communication between the vesicle components and their environment.

Topics & Concepts

NanoporeDNA origamiVesicleSquare (algebra)MembraneNanotechnologyDNAFunction (biology)BiophysicsMaterials scienceChemistryBiologyNanostructureGeometryCell biologyMathematicsBiochemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryNanopore and Nanochannel Transport Studies
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