Latent Autoimmune Diabetes in Adults: A Review of Clinically Relevant Issues
Marta Hernández, Dı́dac Mauricio
Abstract
Latent autoimmune diabetes in adults (LADA) is still a poorly characterized entity. However, its prevalence may be higher than that of classical type 1 diabetes. Patients with LADA are often misclassified as type 2 diabetes. The underlying autoimmune process against β-cell has important consequences for the prognosis, comorbidities, treatment choices and even patient-reported outcomes with this diabetes subtype. However, there is still an important gap of knowledge in many areas of clinical relevance. We are herein focusing on the state of knowledge of relevant clinical issues than may help in the diagnosis and management of subjects with LADA.
Topics & Concepts
Autoimmune diabetesMedicineDiabetes mellitusAutoimmunityImmunologyType 1 diabetesEndocrinologyAntibodyDiabetes and associated disordersDiabetes Management and ResearchPancreatic function and diabetes