The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase
Hundeep Kaur, Roman P. Jakob, Jan K. Marzinek, Robert C. Green, Yu Imai, Jani Reddy Bolla, Elia Agustoni, Carol V. Robinson, Peter J. Bond, Kim Lewis, Timm Maier, Sebastian Hiller
Topics & Concepts
Bacterial outer membraneBiophysicsBacteriaChemistryGram-negative bacteriaMembraneBiologyCell biologyBiochemistryEscherichia coliGeneticsGenePlant biochemistry and biosynthesisEnzyme Structure and FunctionAntibiotic Resistance in Bacteria