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Recent Advancements in Synthesis of Phenanthridines <i>via</i> 2‐Isocyanobiphenyls

Ashutosh Dey, Vikash Kumar, Rana Chatterjee, Ananya Behera, Rohit Maurya, Amarender Goud Burra, Shubham Kumar, Mahender Khatravath, Rambabu Dandella

2023Asian Journal of Organic Chemistry22 citationsDOI

Abstract

Abstract Phenanthridines are a privileged heterocyclic compound that exists in many natural products and has been known to exhibit a variety of pharmacological properties. In the last few decades, an incredible development has taken place to synthesise this scaffold. In this regard, 2‐isocyanobiphenyl has become one of the most exploited substrates that allow the direct formation of phenanthridine derivatives under various novel and conventional methods. The present review provides an overview of synthetic approaches for the preparation of phenanthridine, and their derivatives form 2‐isocyanobiphenyls′′.

Topics & Concepts

PhenanthridineChemistryNanotechnologyCombinatorial chemistryBiochemical engineeringOrganic chemistryEngineeringMaterials scienceChemical synthesis and alkaloidsPhenothiazines and Benzothiazines Synthesis and ActivitiesCatalytic C–H Functionalization Methods
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