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Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells

Qianman Peng, Saud Alqahtani, Mohammed Z. Nasrullah, Jianzhong Shen

2020European Journal of Pharmacology30 citationsDOIOpen Access PDF

Topics & Concepts

Pertussis toxinG proteinGq alpha subunitSignal transductionPhosphorylationReceptorBiologyProtein kinase AForskolinG protein-coupled receptorCell biologyInternal medicineBiochemistryMedicineReceptor Mechanisms and SignalingProtein Kinase Regulation and GTPase SignalingMicrobial Metabolism and Applications
Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells | Litcius