Stereoselective strain-release Ferrier rearrangement: the dual role of catalysts
Huajun Zhang, Aoxin Guo, Han Ding, Yuan Xu, Yuhan Zhang, Dan Yang, Xue‐Wei Liu
Abstract
ACu(OTf) 2 /Fe(OTf) 3 -promoted facile and stereoselective synthesis of 2,3-unsaturated glycosides through Ferrier rearrangement of rationally designed glycals with C3-CCBz. The dual roles of the metal catalysts in the reaction are explored with DFT.
Topics & Concepts
ChemistryStereoselectivityCatalysisDual (grammatical number)GlycosideDual roleCombinatorial chemistryStereochemistryOrganic chemistryArtLiteratureCarbohydrate Chemistry and SynthesisMetalloenzymes and iron-sulfur proteinsLegume Nitrogen Fixing Symbiosis