Molecular Mechanism of Biased Signaling in a Prototypical G-protein-coupled Receptor
Carl‐Mikael Suomivuori, Naomi R. Latorraca, Laura M. Wingler, Stephan Eismann, Matthew C. King, A.L.W. Kleinhenz, Meredith A. Skiba, Dean P. Staus, Andrew C. Kruse, Robert J. Lefkowitz, Ron O. Dror
Topics & Concepts
G protein-coupled receptorAllosteric regulationSignal transductionFunctional selectivitySignaling proteinsMechanism (biology)ReceptorG proteinArrestinIntracellularCell signalingBiologyCell biologyChemistryComputational biologyBiophysicsBiochemistryPhysicsQuantum mechanicsReceptor Mechanisms and SignalingComputational Drug Discovery MethodsMass Spectrometry Techniques and Applications