Pirfenidone promotes the levels of exosomal miR-200 to down-regulate ZEB1 and represses the epithelial-mesenchymal transition of non-small cell lung cancer cells
Jingjing Liu, Liming Cao, Yuanyuan Li, Pengbo Deng, Pinhua Pan, Chengping Hu, Huaping Yang
Topics & Concepts
Epithelial–mesenchymal transitionCancer researchStromal cellCancer-Associated FibroblastsmicroRNALung cancerMesenchymal stem cellTumor microenvironmentChemistryBiologyCancerCell biologyOncologyInternal medicineMedicineMetastasisTumor cellsGeneBiochemistryInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisExtracellular vesicles in diseaseMicroRNA in disease regulation