Dendritic cells can prime anti-tumor CD8+ T cell responses through major histocompatibility complex cross-dressing
Brendan W. MacNabb, Xiufen Chen, Sravya Tumuluru, James L. Godfrey, Darshan N. Kasal, Jovian Yu, Marlieke L.M. Jongsma, Robbert M. Spaapen, Douglas E. Kline, Justin Kline
Topics & Concepts
CD8BiologyMajor histocompatibility complexT cellPriming (agriculture)Cytotoxic T cellAntigen-presenting cellAntigen presentationAntigenCross-presentationImmunologyImmune systemMHC class IGeneticsIn vitroBotanyGerminationImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersCAR-T cell therapy research