Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy
Hua Bai, Yaqi Ding, Xin Li, Deqin Kong, Chenqi Xin, Xuekang Yang, Chengwu Zhang, Zi‐Qiang Rong, Chuanhao Yao, Shenci Lu, Lei Ji, Lin Li, Wei Huang
Topics & Concepts
ParkinATG5AutophagyPINK1MFN2BiologyProgrammed cell deathOxidative stressNeuroprotectionSubstantia nigraCell biologyRotenonemitochondrial fusionMitochondrionParkinson's diseaseMitochondrial DNADopaminergicMitophagyPharmacologyApoptosisMedicineGeneticsBiochemistryEndocrinologyInternal medicineDopamineDiseaseGeneAutophagy in Disease and TherapyParkinson's Disease Mechanisms and TreatmentsSirtuins and Resveratrol in Medicine