Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
Ester Marina-Zárate, Henry J. Sutton, Paul Lopez, Tasha K. Altheide, Michael Bick, Iszac Burton, Elana Ben‐Akiva, Katarzyna Kaczmarek Michaels, Kesha Hyacinth, Brandon S. Healy, Deuk Lim, Lars Hangartner, Dennis R. Burton, Diane G. Carnathan, Guido Silvestri, William R. Schief, Darrell J. Irvine, Shane Crotty
Topics & Concepts
Germinal centerBiologyImmunologyAntibodyPriming (agriculture)CXCR5Memory B cellLymph nodeB cellIsotypeImmunizationFollicular phaseImmune systemLymphNeutralizing antibodyVirologyCellNeutralizationT cellAntigenBCL6Interleukin 9CD40Antibody responseImmunityT helper cellAffinity maturationHIV Research and TreatmentT-cell and B-cell ImmunologyImmunotherapy and Immune Responses