Folate mediated targeted delivery of cinnamaldehyde loaded and FITC functionalized magnetic nanoparticles in breast cancer:<i>in vitro</i>,<i>in vivo</i>and pharmacokinetic studies
Varsha Shetty, Alok P. Jakhade, Kavita Shinde, Rajeev C. Chikate, Ruchika Kaul-Ghanekar
Abstract
FiCF NPs induced apoptosis in breast cancer cells, exhibited safety, reduced tumor burden in mice due to increased pharmacological efficacy.
Topics & Concepts
ChemistryIn vivoIn vitroCinnamaldehydePharmacokineticsBreast cancerPharmacologyNanoparticleNanotechnologyCombinatorial chemistryCancerBiochemistryInternal medicineBiotechnologyCatalysisMaterials scienceMedicineBiologyNanoparticle-Based Drug DeliveryGraphene and Nanomaterials ApplicationsElectrospun Nanofibers in Biomedical Applications