Leveraging Radiobiology for Arrhythmia Management: A New Treatment Paradigm?
D.M. Zhang, Jeffrey J. Szymanski, Carmen Bergom, Phillip S. Cuculich, Clifford G. Robinson, Julie K. Schwarz, Stacey Rentschler
Abstract
Radiation therapy is a well-established approach for safely and non-invasively treating solid tumours and benign diseases with high precision and accuracy. Cardiac radiation therapy has recently emerged as a non-invasive treatment option for the management of refractory ventricular tachycardia. Here we summarise existing clinical and preclinical literature surrounding cardiac radiobiology and discuss how these studies may inform basic and translational research, as well as clinical treatment paradigms in the management of arrhythmias.
Topics & Concepts
MedicineRadiobiologyRadiation therapyVentricular tachycardiaIntensive care medicineMedical physicsInternal medicineCardiac electrophysiology and arrhythmiasCardiac Arrhythmias and TreatmentsCardiovascular Effects of Exercise