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Role of ferroptosis in promoting cardiotoxicity induced by Imatinib Mesylate via down-regulating Nrf2 pathways in vitro and in vivo

Chengzhu Song, Dongning Li, Jie Zhang, Xiaoyan Zhao

2021Toxicology and Applied Pharmacology28 citationsDOI

Topics & Concepts

CardiotoxicityIn vivoImatinib mesylatePharmacologyChemistryReactive oxygen speciesApoptosisViability assayGlutathioneMitochondrionMyeloid leukemiaToxicityBiochemistryCancer researchImatinibMedicineBiologyEnzymeBiotechnologyOrganic chemistryCancer, Lipids, and MetabolismKruppel-like factors researchFerroptosis and cancer prognosis
Role of ferroptosis in promoting cardiotoxicity induced by Imatinib Mesylate via down-regulating Nrf2 pathways in vitro and in vivo | Litcius