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Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial

Deborah B. Horn, Donna H. Ryan, Sanja Giljanovic Kiš, Breno Edson Sendão Alves, Mu Yiming, Sin Gon Kim, Jens Aberle, Stephen C. Bain, Sheryl Allen, Elizabeth B. Sarker, Qiwei Wu, Adam Stefański, Irina Jouravskaya

2025The Lancet26 citationsDOI

Topics & Concepts

MedicineType 2 diabetesObesityInternal medicineDiabetes mellitusReceptorEndocrinologyPhase (matter)Clinical trialPhases of clinical researchMEDLINEDiabetes Treatment and ManagementRegulation of Appetite and ObesityMetabolism, Diabetes, and Cancer
Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial | Litcius