Role of the <i>fsr</i> Quorum-Sensing System in Enterococcus faecalis Bloodstream Infection
Jinglin Yue, Mingxi Hua, Nan Chen, Jiarui Li, Xinzhe Liu, Ang Duan, Huizhu Wang, Pengcheng Du, Chengbo Rong, Duo Yang, Chen Chen
Abstract
First, we conducted an advanced study on the genomic differences between colonizing and infecting E. faecalis , which provides support and evidence for early and accurate diagnoses. Second, we discovered that fsr was significantly associated with blood infections, which also provides additional information for studies exploring the invasiveness of E. faecalis . Most importantly, we found that fsr played an important role in both biofilm formation and serum resistance ability in E. faecalis .
Topics & Concepts
Enterococcus faecalisMicrobiologyQuorum sensingBiologyBiofilmBloodstream infectionEnterococcusStreptococcaceaeBacteriaStaphylococcus aureusGeneticsAntibioticsAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingStreptococcal Infections and Treatments