Functional Validation of the RQR8 Suicide /Marker Gene in CD19 CAR-T Cells and CLL1CAR-T Cells
Xia Xiong, Yibing Yu, Xin Jin, Danni Xie, Rui Sun, Wenyi Lu, Yunxiong Wei, Ruiting Guo, Mingfeng Zhao
Topics & Concepts
Suicide geneChimeric antigen receptorCD19CD20EpitopeImmunologyAdoptive cell transferAntigenCytotoxic T cellImmunotherapyCancer researchMedicineGenetic enhancementT cellBiologyImmune systemIn vitroGeneBiochemistryCAR-T cell therapy researchVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects