Copper-Catalyzed Disulfonation of Terminal Alkynes with Sodium Arylsulfinates
Zhenhua Liu, Lin Yang, Kaining Zhang, Wanjiao Chen, Yu Tian, Lianxiao Wang, Wen Gao, Bo Tang
Abstract
A novel and direct disulfonylation reaction of commercially available terminal alkynes under copper(I)/bromodifluoroacetate cocatalyst has been realized. This protocol provides a facile and practical pathway to selectively access (E)-1,2-disulfonylethenes, in which features good functional group compatibility, easily available starting materials, and excellent stereoselectivity with good yields.
Topics & Concepts
ChemistryStereoselectivityCompatibility (geochemistry)CopperCatalysisTerminal (telecommunication)Combinatorial chemistryFunctional groupSodiumOrganic chemistryChemical engineeringComputer scienceComputer networkPolymerEngineeringSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods