Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway
Yi Yu, Jingwei Liang, Zhexin Yuan, Aiping Wang, Xinxing Liu, Yu Chen, Min Zhang, Yanan Gao, Haiying Zhang, Yan Liu, Haiying Zhang, Yan Liu
Topics & Concepts
Lipid peroxidationChemistryCCL4Gene knockdownLiver injuryPharmacologyGCLCOxidative stressWestern blotAntioxidantAndrographolideApoptosisBiochemistryBiologyGlutathioneEnzymeCarbon tetrachlorideGeneOrganic chemistryMedicinal Plant StudiesHeme Oxygenase-1 and Carbon MonoxideGenomics, phytochemicals, and oxidative stress