Non-viral nitric oxide-based gene therapy improves perfusion and liposomal doxorubicin sonopermeation in neuroblastoma models
Aditi Bellary, Chance M. Nowak, Isabella Iwanicki, Fernando Flores-Guzmán, Lydia Wu, Jessica J. Kandel, Theodore W. Laetsch, Leonidas Bleris, Sonia L. Hernandez, Shashank R. Sirsi
Abstract
, allowing the identification of an ideal time-point to administer therapy.
Topics & Concepts
MicrobubblesIn vivoGenetic enhancementCancer researchMedicineTransfectionDoxorubicinPerfusionNeuroblastomaNitric oxideNitric oxide synthaseGene deliveryPharmacologyPathologyUltrasoundChemistryBiologyInternal medicineChemotherapyCell cultureGeneRadiologyBiochemistryGeneticsBiotechnologyNeuroblastoma Research and TreatmentsUltrasound and Hyperthermia ApplicationsNanoplatforms for cancer theranostics