Time-resolved SANS reveals pore-forming peptides cause rapid lipid reorganization
Michael H. L. Nguyen, Mitchell DiPasquale, Brett W. Rickeard, Caesar G. Yip, Kaity N. Greco, Elizabeth G. Kelley, Drew Marquardt
Abstract
Time-resolved SANS showed alamethicin and melittin promote DMPC lipid vesicle mixing and perturb DMPC kinetics in similar ways.
Topics & Concepts
ChemistryAlamethicinMelittinVesicleKineticsBiophysicsLipid bilayerCrystallographyPeptideMembraneBiochemistryQuantum mechanicsBiologyPhysicsLipid Membrane Structure and BehaviorAntimicrobial Peptides and ActivitiesRNA Interference and Gene Delivery