Assessing the In Vitro Antioxidant and Anti-inflammatory Activity of Moringa oleifera Crude Extract
Rajesh Kumar, Sheeja Varghese, Shanmugapriya Ramamurthy, Saranya Varadarajan, Thodur Madapusi Balaji, B Prem Karthick, Kavitha Thiagarajan
Abstract
BACKGROUND: Chronic inflammation and oxidative stress play a vital role in the pathogenesis of various diseases of the oral cavity including periodontal disease. Phytochemicals present in plants with antioxidant (AO) and anti-inflammatory properties could aid as a therapeutic adjunct in the management of these diseases. AIM: environment. MATERIALS AND METHODS: Lam. were prepared by maceration. Antioxidant activity was assessed by FRAP, hydroxyl radical scavenging activity, and DPPH radical scavenging assay. Anti-inflammatory activity was assessed by Albumin Denaturation Assay. Experiments were repeated thrice, and mean and standard deviation were calculated. RESULTS: Both the test substances exhibited significant antioxidant and anti-inflammatory activity, and aqueous extracts exhibited higher activity than ethanolic extract. SUMMARY AND CONCLUSION: Lam. could be further explored for the management of periodontal disease as a local drug delivery system with the extract could be developed.