ABCB1 c.2677G>T/c.3435C>T diplotype increases the early-phase oral absorption of losartan
Hyo-Bin Shin, Eui Hyun Jung, Pureum Kang, Chang Woo Lim, Kyung-Yul Oh, Chang‐Keun Cho, Yun Jeong Lee, Chang‐Ik Choi, Choon‐Gon Jang, Seok‐Yong Lee, Jung‐Woo Bae
Topics & Concepts
LosartanCmaxPharmacokineticsPharmacologyChemistryUrineCYP3A4Absorption (acoustics)MedicineAngiotensin IICytochrome P450MetabolismBiochemistryReceptorAcousticsPhysicsDrug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesHIV/AIDS drug development and treatment