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Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system

Jing Zhang, Benjamin Buller, Zheng Gang Zhang, Yi Zhang, Mei Lü, Douglas L. Rosene, Maria Medalla, Tara L. Moore, Michael Chopp

2021Experimental Neurology187 citationsDOI

Topics & Concepts

RemyelinationMesenchymal stem cellMultiple sclerosisExperimental autoimmune encephalomyelitisNeuroinflammationMicrovesiclesMedicineOligodendrocyteBone marrowImmunologyCentral nervous systemDemyelinating diseaseNeural stem cellMicrogliaDemyelinating DisorderMyelinStem cellBiologyPathologyCell biologyInflammationInternal medicineGenemicroRNABiochemistryExtracellular vesicles in diseaseMicroRNA in disease regulationNeurogenesis and neuroplasticity mechanisms
Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system | Litcius