Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway
Zhengmei Xia, Cheng Zhang, Chunyu Guo, Bingdong Song, Weirong Hu, Yingying Cui, Yanni Xue, Mi‐Zhen Xia, De‐Xiang Xu, Shichen Zhang, Jun Fang
Topics & Concepts
InflammasomeSMADFibrosisKidneyPharmacologyMedicineNephrotoxicityDownregulation and upregulationCancer researchTransforming growth factorInternal medicineChemistryInflammationBiochemistryGeneHeme Oxygenase-1 and Carbon MonoxideNeonatal Health and BiochemistryInflammasome and immune disorders