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Hetero-Diels–Alder reactions of (isobenzo)furans

Christopher J. DeAngelis, Christopher G. Newton

2025Organic & Biomolecular Chemistry7 citationsDOIOpen Access PDF

Abstract

Hetero-Diels-Alder reactions of furans and isobenzofurans provide convergent redox-neutral access to hetero-oxanorbornene derivatives. These versatile intermediates serve as precursors to a variety of heterocycles, polymers, and complex natural products. Herein we comprehensively review this area of research and speculate on what developments are required to advance the field.

Topics & Concepts

Diels–Alder reactionAlderOrganic chemistryChemistryCatalysisBiologyEcologyCatalytic Alkyne ReactionsOxidative Organic Chemistry ReactionsSynthetic Organic Chemistry Methods
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