Low-dose naltrexone inhibits colorectal cancer progression and promotes apoptosis by increasing M1-type macrophages and activating the Bax/Bcl-2/caspase-3/PARP pathway
Mingxing Ma, Xiaonan Wang, Ning Liu, Fengping Shan, Yong Feng
Topics & Concepts
SurvivinApoptosisCancer researchDownregulation and upregulationTumor necrosis factor alphaColorectal cancerMedicineCaspase 3BiologyCancerImmunologyProgrammed cell deathInternal medicineBiochemistryGeneCancer, Stress, Anesthesia, and Immune ResponseImmune cells in cancerNeuropeptides and Animal Physiology