Rapid response to spesolimab in a patient with severe refractory pyoderma gangrenosum
Ma Li, Xiaohong Chen, Qing Guo, Zhuhui Qiao, Nansong Wang, Pearl Pai, Xiaoming Liu
Abstract
We report on a patient with severe ulcerative pyoderma gangrenosum that was recalcitrant to systemic corticosteroid, tumour necrosis factor antagonist and ciclosporin treatment and finally controlled when spesolimab was added to the treatment regimen.
Topics & Concepts
Pyoderma gangrenosumMedicineCiclosporinRefractory (planetary science)CorticosteroidRegimenDermatologySurgeryChemotherapyInternal medicineDiseaseAstrobiologyPhysicsAutoimmune and Inflammatory DisordersHidradenitis Suppurativa and TreatmentsOral Health Pathology and Treatment