Litcius/Paper detail

Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases

Klara Kulenkampff, Adriana-M. Wolf Perez, Pietro Sormanni, Johnny Habchi, Michele Vendruscolo

2021Nature Reviews Chemistry114 citationsDOI

Topics & Concepts

Protein aggregationOligomerProtein foldingDiseaseAmyloid (mycology)Computational biologyMechanism (biology)NeurodegenerationDrug discoveryConfusionNeuroscienceMedicineBiologyBioinformaticsChemistryBiochemistryPathologyPsychologyPhilosophyPsychoanalysisOrganic chemistryEpistemologyAlzheimer's disease research and treatmentsProtein Structure and DynamicsComputational Drug Discovery Methods