Virus-assisted directed evolution of enhanced suppressor tRNAs in mammalian cells
Delilah Jewel, Rachel E. Kelemen, Rachel L. Huang, Zeyu Zhu, Bharathi Sundaresh, Xiaofu Cao, Kaitlin Malley, Zeyi Huang, Muhammad Pasha, Jon Anthony, Tim van Opijnen, Abhishek Chatterjee
Topics & Concepts
Transfer RNABiologyMutantAmino acidTranslation (biology)Aminoacyl tRNA synthetaseProtein biosynthesisEscherichia coliAmino Acyl-tRNA SynthetasesDirected evolutionRibosomeSynthetic biologySuppressor mutationRNABiochemistryCell biologyGeneticsGeneMessenger RNARNA and protein synthesis mechanismsRNA modifications and cancerRNA Research and Splicing