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Hyaluronic acid/serotonin-decorated cerium dioxide nanomedicine for targeted treatment of ulcerative colitis

Yanyao Gao, Jing Zou, Bo Chen, Yuhao Cao, Datao Hu, Yuchen Zhang, Xinxin Zhao, Jinpeng Wen, Kailai Liu, Ke Wang

2022Biomaterials Science39 citationsDOI

Abstract

is a promising novel drug for the treatment of ulcerative colitis. In addition to illustrating the benefits of this novel nanodrug delivery in treating ulcerative colitis compared to traditional medications, this study provides theoretical and experimental support for its application to any targeted therapy for ulcerative colitis.

Topics & Concepts

Ulcerative colitisMyeloperoxidaseHyaluronic acidColitisInflammatory bowel diseasePharmacologyInflammationTargeted drug deliveryReactive oxygen speciesMedicineChemistryDrugNanomedicineImmunologyInternal medicineBiochemistryDiseaseAnatomyMaterials scienceNanotechnologyNanoparticleAdvanced Nanomaterials in CatalysisNeutrophil, Myeloperoxidase and Oxidative MechanismsNanoplatforms for cancer theranostics
Hyaluronic acid/serotonin-decorated cerium dioxide nanomedicine for targeted treatment of ulcerative colitis | Litcius