Nutrition and Markers of Disease Severity in Patients With Bronchiectasis
Katherine A. Despotes, Radmila Choate, Doreen Addrizzo‐Harris, Timothy R. Aksamit, Alan R. Barker, Ashwin Basavaraj, Charles L. Daley, Edward Eden, Angela DiMango, Kevin P. Fennelly, Julie V. Philley, Margaret M. Johnson, Pamela J. McShane, Mark L. Metersky, Anne E. O’Donnell, Kenneth N. Olivier, Matthias Salathé, Andreas Schmid, Byron Thomashow, Gregory Tino, Kevin Winthrop, Michael R. Knowles, M. Leigh Anne Daniels, Peadar G. Noone
Abstract
BACKGROUND: Increasing numbers of patients are being diagnosed with bronchiectasis, yet much remains to be elucidated about this heterogeneous patient population. We sought to determine the relationship between nutrition and health outcomes in non-cystic fibrosis (non-CF) bronchiectasis, using data from the U.S. Bronchiectasis Nontuberculous Mycobacterial Research Registry (U.S. BRR). METHODS: This was a retrospective, observational, longitudinal study using 5-year follow-up data from the BRR. Bronchiectasis was confirmed on computed tomography (CT). We stratified patients into nutrition categories using body mass index (BMI), and correlated BMI to markers of disease severity. RESULTS: , non-tuberculous mycobacteria, or by cause of bronchiectasis. The majority of patients demonstrated stable BMI over 5 years. CONCLUSIONS: Although underweight patients with bronchiectasis have lower lung function, lower BMI does not appear to relate to other markers of disease severity in this patient population.