Tongqiao Huoxue Decoction inhibits ferroptosis by facilitating ACSL4 ubiquitination degradation for neuroprotection against cerebral ischemia-reperfusion injury
Zhijie Ou, Yanting Deng, Yan Wu, Yuanqi Wang, Yijing Zhao, Chang Liu, Zhuoyu Wang, Manhua Liu, Xin Hu, Li Fang, Juping Chen
Topics & Concepts
NeuroprotectionPharmacologyIschemiaMalondialdehydeSuperoxide dismutaseWestern blotReactive oxygen speciesDecoctionCerebral infarctionIn vivoReperfusion injuryMedicineStroke (engine)Brain ischemiaBrain damageOxidative stressChemistryTraditional medicineBiochemistryBiologyInternal medicineMechanical engineeringBiotechnologyEngineeringGeneFerroptosis and cancer prognosisImmune cells in cancerInflammasome and immune disorders