PVA/κ-carrageenan/Au/camptothecin/pegylated-polyurethane/paclitaxel nanofibers against lung cancer treatment
Mohammad Irani, Sina Mohammadrezaei Nodeh
Abstract
antitumor activity results confirmed the synergic effect of Au, CMPT and PTX anticancer drugs on the reduction of tumor volume without change in mouse weight by the PVA/κ-carrageenan/CMPT/Au/pegylated PU/PTX core-shell nanofibers. The obtained results indicated that the simultaneous loading of CMPT and PTX anticancer drugs and Au nanoparticles is more beneficial for lung cancer treatment.
Topics & Concepts
CamptothecinPaclitaxelNanofiberLung cancerCarrageenanPolyurethaneChemistryMaterials scienceMedicinePharmacologyCancerNanotechnologyOncologyOrganic chemistryInternal medicineElectrospun Nanofibers in Biomedical ApplicationsNanoplatforms for cancer theranosticsGraphene and Nanomaterials Applications