Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6
Diego Méndez, Félix A. Urra, Juan Pablo Millas-Vargas, Marcelo Alarcón, Julio Rodríguez-Lavado, Iván Palomo, Andrés Trostchansky, Ramiro Araya‐Maturana, Eduardo Fuentes
Topics & Concepts
ChemistryPlateletAgonistPlatelet activationHydroquinoneAdenosine diphosphateCytotoxicityThrombinP2Y12Platelet aggregation inhibitorStereochemistryBiophysicsBiochemistryPharmacologyReceptorIn vitroPlatelet aggregationAspirinInternal medicineBiologyClopidogrelMedicineAntiplatelet Therapy and Cardiovascular DiseasesSynthesis of β-Lactam CompoundsNatural Compounds in Disease Treatment