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STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma

Wanli Yu, Shikai Gui, Lunshan Peng, Haitao Luo, Jiabao Xie, Juexian Xiao, Yimuran Yilamu, Yi Sun, Shihao Cai, Zujue Cheng, Zhennan Tao

2025Developmental Cell30 citationsDOI

Topics & Concepts

BiologyImmune systemGlioblastomaPositive feedbackFeedback loopCell biologyComputational biologyCancer researchImmunologyEngineeringComputer securityComputer scienceElectrical engineeringExtracellular vesicles in diseaseinterferon and immune responsesImmune cells in cancer
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma | Litcius