<i>N</i>,<i>C</i>-Coupled naphthylisoquinoline alkaloids: a versatile new class of axially chiral natural products
Nasir Tajuddeen, Gerhard Bringmann
Abstract
This is the first review on the new subclass of N , C -coupled NIQs, their isolation and structural elucidation, their N , C -axial chirality, their biosynthetic origin, their promising antiparasitic and antileukemia activities, and their total synthesis.
Topics & Concepts
Chirality (physics)StereochemistrySubclassAxial symmetryTotal synthesisClass (philosophy)Axial chiralityChemistryAntiparasiticCombinatorial chemistryPhysicsBiologyEnantioselective synthesisOrganic chemistryComputer scienceChiral symmetryGeneticsCatalysisMedicineArtificial intelligencePathologyQuarkQuantum mechanicsAntibodyNambu–Jona-Lasinio modelAxial and Atropisomeric Chirality SynthesisMolecular spectroscopy and chiralityBioactive Compounds and Antitumor Agents