Mapping kidney tubule diameter ex vivo by diffusion MRI
Darya Morozov, Neda Parvin, Jennifer R. Charlton, Kevin M. Bennett
Abstract
Tubular pathologies are a common feature of kidney disease. Current metrics to assess kidney health, in vivo or in transplant, are generally based on urinary or serum biomarkers and pathological findings from kidney biopsies. Diffusion MRI can be used to measure the distribution of tubule diameters in the kidney cortex ex vivo and may provide a new noninvasive biomarker of tubular pathology.
Topics & Concepts
Ex vivoKidneyPathologyIn vivoMedicineMagnetic resonance imagingBiologyRadiologyInternal medicineBiotechnologyMRI in cancer diagnosisAdvanced Neuroimaging Techniques and ApplicationsFetal and Pediatric Neurological Disorders