Intestinal Efflux Transporters P-gp and BCRP Are Not Clinically Relevant in Apixaban Disposition
Jasleen K. Sodhi, Shuaibing Liu, Leslie Z. Benet
Topics & Concepts
ApixabanEffluxAbcg2PharmacologyTransporterATP-binding cassette transporterDrugChemistryMedicineBiochemistryRivaroxabanInternal medicineGeneAtrial fibrillationWarfarinDrug Transport and Resistance MechanismsPharmacogenetics and Drug MetabolismGastroesophageal reflux and treatments