Salbutamol delivery in small children: Effect of valved holding chamber and breathing patterns
Laura Ojanperä, Lauri Lehtimäki, Balázs Kelemen, Péter Csonka
Abstract
Delivering inhaled medication in preschool children is challenging due to lack of co-operation, variable respiratory rate (RR), and low tidal volume (Vt). The breathing parameters are influenced by factors such as age, development, and the severity of bronchial obstruction, which, in turn, affect the delivery and response to medication.1
Topics & Concepts
MedicineSalbutamolParticle sizeAnesthesiaBreathingChromatographyInternal medicineAsthmaChemical engineeringEngineeringChemistryPharmacological Effects and AssaysInhalation and Respiratory Drug DeliveryAsthma and respiratory diseases